Susan A Charman Selected Research

sulfoxide

8/2014

Antitrypanosomal activity of fexinidazole metabolites, potential new drug candidates for Chagas disease.

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Susan A Charman Research Topics

Disease

38	Malaria 05/2024 - 08/2004
13	Neoplasms (Cancer) 10/2023 - 08/2009
9	Infections 10/2023 - 05/2014
7	Chagas Disease (American Trypanosomiasis) 12/2020 - 05/2012
5	Parasitemia 01/2021 - 09/2012
3	Autoimmune Diseases (Autoimmune Disease) 12/2022 - 06/2014
3	Falciparum Malaria (Plasmodium falciparum Malaria) 01/2017 - 07/2006
2	Breast Neoplasms (Breast Cancer) 10/2023 - 12/2021
2	Schistosomiasis (Bilharziasis) 10/2023 - 10/2020
2	Parkinson Disease (Parkinson's Disease) 09/2021 - 01/2017
1	Visceral Leishmaniasis (Kala Azar) 12/2023
1	Severe Dengue 07/2023
1	Hypoxia (Hypoxemia) 01/2022
1	COVID-19 01/2022
1	Tuberculosis (Tuberculoses) 12/2021
1	Drug-Related Side Effects and Adverse Reactions 12/2021
1	Neglected Diseases 10/2020
1	Neoplasm Metastasis (Metastasis) 01/2019
1	Lymphoma (Lymphomas) 01/2018
1	Hepatocellular Carcinoma (Hepatoma) 01/2018
1	Severe Combined Immunodeficiency (Bare Lymphocyte Syndrome) 01/2018
1	Persistent Infection 10/2016
1	Body Weight (Weight, Body) 09/2015

Drug/Important Bio-Agent (IBA)

19	Antimalarials (Antimalarial Agents)IBA 05/2024 - 08/2004
9	EnzymesIBA 12/2022 - 06/2012
7	Dihydroorotate DehydrogenaseIBA 12/2022 - 06/2014
6	artemisinin (artemisinine)IBA 05/2024 - 08/2004
6	1,2,4-trioxaneIBA 01/2021 - 03/2011
5	DSM265IBA 01/2021 - 07/2015
4	pyrimidineIBA 12/2022 - 07/2015
4	Carbonic Anhydrases (Carbonic Anhydrase)IBA 12/2013 - 10/2009
3	Heme (Haem)IBA 11/2021 - 08/2004
3	IronIBA 09/2021 - 01/2017
3	Proteins (Proteins, Gene)FDA Link 01/2020 - 01/2015
3	PeroxidesIBA 01/2020 - 07/2006
3	benzonidazole (benznidazole)IBA 10/2016 - 09/2012
3	ProdrugsIBA 09/2015 - 09/2011
3	SulfonamidesIBA 12/2013 - 10/2009
3	IsoenzymesIBA 06/2012 - 10/2009
2	Complement System Proteins (Complement)IBA 05/2024 - 12/2021
2	Lysine AcetyltransferasesIBA 10/2023 - 01/2020
2	Praziquantel (Biltricide)FDA Link 10/2023 - 10/2020
2	8-hydroxyquinazolin-4(3H)-oneIBA 09/2021 - 01/2017
2	alpha-SynucleinIBA 09/2021 - 01/2017
2	ArtesunateIBA 01/2019 - 08/2004
2	alpha-aminopyridineIBA 01/2018 - 01/2017
2	MMV390048IBA 01/2018 - 01/2017
2	NifurtimoxIBA 10/2016 - 01/2015
2	fexinidazoleIBA 10/2016 - 08/2014
2	SulfonesIBA 10/2016 - 08/2014
2	6- Chloro- 7- methoxy- 2- methyl- 3- (4- (4- (trifluoromethoxy)phenoxy)phenyl)quinolin- 4(1H)- oneIBA 09/2015 - 03/2013
2	QuinolonesIBA 05/2014 - 09/2012
2	fenarimolIBA 12/2013 - 05/2012
2	SterolsIBA 11/2013 - 09/2012
2	Tubulin ModulatorsIBA 09/2011 - 08/2009
2	CYT997IBA 11/2009 - 08/2009
1	acetamideIBA 03/2024
1	Electron Transport Complex III (Coenzyme Q-Cytochrome-c Reductase)IBA 12/2023
1	RNA Polymerase II (RNA Polymerase B)IBA 10/2023
1	Estrogens (Estrogen)FDA Link 10/2023
1	Histones (Histone)IBA 10/2023
1	Histone Acetyltransferases (Histone Acetyltransferase)IBA 10/2023
1	LipidsIBA 07/2023
1	FenretinideIBA 07/2023
1	Anti-Bacterial Agents (Antibiotics)IBA 01/2022
1	Antiviral Agents (Antivirals)IBA 01/2022
1	Oxygen (Dioxygen)IBA 01/2022
1	Isoniazid (Ftivazide)FDA LinkGeneric 12/2021
1	taxaneIBA 12/2021
1	5-(N,N-hexamethylene)amilorideIBA 01/2021
1	Amiloride (Midamor)FDA LinkGeneric 01/2021
1	TriazinesIBA 01/2021
1	Urokinase-Type Plasminogen Activator (Urokinase)FDA Link 01/2021
1	Plasminogen Activators (Plasminogen Activator)IBA 01/2021
1	DiureticsIBA 01/2021
1	pretomanidIBA 12/2020
1	NitroimidazolesIBA 12/2020
1	AntigensIBA 08/2020
1	PyrrolesIBA 01/2020
1	artefenomelIBA 01/2020
1	arterolaneIBA 01/2020
1	CarbonIBA 12/2019
1	ZincIBA 01/2019
1	AminopeptidasesIBA 01/2019
1	CD13 Antigens (Alanine Aminopeptidase)IBA 01/2019
1	proguanil drug combination atovaquone (malarone)FDA Link 11/2018
1	1-Phosphatidylinositol 4-Kinase (1 Phosphatidylinositol 4 Kinase)IBA 01/2018
1	2- Fluoro- N'- (3- fluoro- 5- (pyridin- 2- yl)benzoyl)benzenesulfonohydrazideIBA 01/2018
1	2-(phenylsulfonyl)hydrazide 4-fluoro-5-methyl- (1,1'-Biphenyl)-3-carboxylic acidIBA 01/2018
1	LigandsIBA 01/2017
1	2-aminopyrazineIBA 11/2016
1	Mefloquine (Lariam)FDA LinkGeneric 11/2015
1	Drug CombinationsIBA 07/2015
1	Guanosine Triphosphate (GTP)IBA 01/2015
1	Messenger RNA (mRNA)IBA 01/2015
1	DDD107498IBA 01/2015

Therapy/Procedure

9	Therapeutics 05/2024 - 06/2011
3	Drug Therapy (Chemotherapy) 12/2021 - 08/2004
3	Oral Administration 01/2019 - 08/2014
1	Duration of Therapy 10/2016